Piero Donini, a scientist working in the late 1940s for the Italian pharmaceutical company that would later be known as Serono, was the first to extract and purify FSH and LH, the hormones that stimulate ovulation. The hormones are found in women’s urine, which is why pregnancy tests can be conducted on urine samples. After experimenting with urine from pregnant women, Donini discovered the highest levels of the hormone actually were in post-menopausal women. After menopause, when ovaries stop producing eggs, FHS and LS shoot up as the body tries to stimulate their production.