After more than 5 years of follow-up, women who received a gonadotropin-releasing hormone agonist (GnRHa) did not have higher rates of ovarian reserve or pregnancy, as compared with women who received chemotherapy without the GnRHa. Premature ovarian failure had significant associations with patient age, the conditioning regimen for hemopoietic stem cell transplant, and cumulative dose of cyclophosphamide but not the use of a GnRHa, as reported online in the Journal of Clinical Oncology.
Tag: stem cell
Human Stem Cell With Half a Genome Could Help Infertile Couples
Sometimes less is more. Scientists have created a new kind of human stem cell that has just half a genome. The cells can be turned into any tissue in the human body, despite only containing one set of chromosomes. The discovery will provide a vital tool for developing therapies to treat a range of conditions, including cancer and infertility, and may even shed light on why we reproduce sexually via two parents rather than one.
Changes in Metabolites Can Regulate Earliest Stages of Development
Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.
New Type of Stem Cell May Make Study of Human Embryos Easier
Scientists have found a new type of stem cell, one that can develop into any kind of tissue in the body, that may make research on early embryonic cell states easier — and could lead to new research opportunities for developmental disorders.
European Union Debates Initiative on Embryo Protection
A packed hearing on a petition calling for the protection of human embryos led to a rare outbreak of raucous exchanges in the European Parliament on Thursday — a sign that the battles over abortion and stem cell research that divide nations like Spain and the United States are making a serious incursion into European Union affairs.
Abortion Viewed in Moral Terms: Fewer See Stem Cell Research and IVF as Moral Issues
Regardless of their views about the legality of abortion, most Americans think that having an abortion is a moral issue. By contrast, the public is much less likely to see other issues involving human embryos – such as stem cell research or in vitro fertilization – as a matter of morality.
Japanese Scientists to Grow Human Organs in Animals
Japanese scientists have developed a process for forming a chimeric embryo by planting a human stem cell into an animal embryo, usually a pig. The organs would then mature inside the animal until scientists harvest and transplant them into a human body.
Alan Trounson, California’s Doctor Stem Cell
In 2004, with President George W. Bush dead set against stem cell research, California just went ahead and did it. Voters made stem cell research a state constitutional right, and endorsed $3 billion in bond sales for 10 years to cement the deal. CIRM, the California Institute for Regenerative Medicine created under Proposition 71, has become a world center for stem cell research, and its president is Australian Alan Trounson, a pioneer in in vitro fertilization. As Proposition 71 approaches its 10-year anniversary, Trounson offers a prognosis.
Human Embryonic Stem Cell Study Under Investigation
A group of anonymous scientists has voiced concerns about a controversial stem cell finding published online in Cell earlier this month, causing the journal to begin an investigation.
US Appeals Court Panel Rules Federal Funding of Human Embryonic Stem Cell Research Is Allowed by Law
This morning, a three judge Federal Appeals Court panel unanimously affirmed a lower court decision in Sherley v. Sebelius, allowing NIH funding of human embryonic stem cell research to continue.