There is a much disputed claim that “injury” to the lining of the uterus — whether inadvertent or deliberate — increases the chance of embryo implantation and thus the chance of pregnancy in certain groups of women having IVF. The “injury” has usually been performed as a biopsy from the womb lining (endometrium), whose action is believed to cause a favourable inflammation (“scratch”) within the endometrium thereby making it more receptive to an implanting embryo. Indeed, the success of more complex uterine surgery in some studies has even been attributed to the scratch and not to the surgery itself.
Tag: implantation
Why Is The Scientific World Abuzz About An Unpublished Paper? Because It Could Permanently Change Human DNA
Scientists around the world are anticipating the results of a Chinese study that would mark the first time DNA in a human embryo has been modified in a way that would carry into future generations. Although the embryos would be for study only, and not intended for implantation, the research would mark a significant milestone: the first time human DNA had been altered so substantially that it would change the “germ line” — the eggs or sperm of any child produced from the embryo.
Gene Crucial For Embryo Implantation Discovered; May Offer Important Insight Into Variety Of Infertility Issues
A study led by researchers from the Cincinnati Children’s Hospital Medical Center has identified a crucial molecular key to healthy embryo implantation and pregnancy. The gene, called Wnt5a, was found to be absolutely critical for the healthy embryo implantation in the uterus wall, according to a press release.
Severe Endometriosis Associated with Poor IVF Outcomes
This study found that women with endometriosis experienced a higher incidence of adverse IVF outcomes. Major findings include the observed association between advanced endometriosis (Stage III/IV) and lower rates of implantation and clinical pregnancy
IVF Clinic Deploys Ion Torrent Sequencing in Embryo Screening
A reproductive clinic in New Jersey has successfully used next-generation sequencing (NGS) to screen embryos conceived in otherwise routine in vitro fertilization (IVF) cases prior to implantation.