It is a biological fact that female fertility declines with age – in assisted conception as in natural. Indeed, findings from a 12-year study reported today at the Annual Meeting of ESHRE by Dr Marta Devesa from the Hospital Universitaro Quiron-Dexeus in Barcelona, Spain, showed that in her own clinic cumulative live birth rates following IVF declined from 23.6% in women aged 38-39 years to 1.3% in those aged 44 and over.