The impact of ART in a fertile setting cannot be studied because otherwise fertile women cannot be randomly assigned to IVF treatment due to ethical concerns. Recent advances in technology, however, could present an opportunity. Couples with proven fertility may elect to undergo preimplantation genetic testing, and the perinatal outcome of these pregnancies could be used to evaluate an unstudied group: fertile women utilizing ART. An adverse impact observed among them could represent the adverse impact of ART itself.
Effect of Fertility on Perinatal Outcomes
