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Appendectomies No Threat to Fertility, Study Says

Getting an appendectomy doesn’t seem to hurt a woman’s chance of having babies, according to a new study that contradicts long-held beliefs among fertility experts.

In fact, UK researchers found women who’d had their appendix removed were more likely to get pregnant later on than women who hadn’t had the common surgery.

Dr. Alan B. Copperman, who heads the division of reproductive endocrinology at Mount Sinai Medical Center in New York and was not involved in the new work, called the results “reassuring.”

“We always assume that appendectomy is a risk factor for infertility,” he told Reuters Health. “This study showed us it wasn’t necessarily the appendectomy that put patients at risk.”

Still, he warned, “I would not conclude that your fertility is enhanced by appendectomy.”

The procedure is one of the most common surgeries in the U.S. and is usually done to treat appendicitis, a potentially life-threatening inflammation of the appendix.

One in 14 people nationally will have appendicitis at some point in their life. It most commonly occurs in young people age 10 to 30.

Ruptured appendixes and bad pelvic infections after appendectomies are known to increase the risk of infertility. Some reports have also suggested the appendectomy itself might hurt a woman’s fertility, presumably because it could leave scar tissue sticking to the fallopian tubes, snagging the egg on its way to the uterus.

“A lot of patients thought they would become infertile after appendicectomy (appendectomy),” said Dr. Sami Shimi, a surgeon at the University of Dundee in Scotland, who worked on the new study. “But when I looked at the reports supporting this, they were really weak.”

He and his colleagues decided to do a bigger study, using a limited patient database. They were taken aback by the results.

“I was completely surprised that patients who had had an appendicectomy or appendicitis were more fertile, they had more subsequent pregnancies,” Shimi told Reuters Health. “And I thought, OK, I have done something wrong here.”

So the team tapped into one of the world’s largest digital repositories of medical records from primary care, the General Practice Research Database from the UK.

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Continued Infertility Treatments Drive Pregnancy Successes

Women in their 30s and 40s who undergo multiple infertility treatments may be nearly as likely to deliver a baby as women who conceive naturally, according to new research that provides men and women with a more realistic view of their chances of becoming parents.

Until now, the success of in vitro fertilization and other assisted reproductive technology (ART) was based on live births following a single course of treatment, called a cycle. However, researchers for the first time have calculated cumulative success rates for women undergoing several treatment cycles. Among nearly 250,000 U.S. women treated with ART in 2004-2009, 57 percent achieved a live birth, they reported. In addition, 30 percent of all ART cycles were successful, they found.

“This study shows that if you keep at it …your chances of becoming pregnant continue to rise with continuing treatment,” said lead researcher Barbara Luke, a professor of obstetrics, gynecology and reproductive biology at Michigan State University’s College of Human Medicine in Lansing. “The takeaway message from this is you may need to look at infertility treatment over a course of cycles.”

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Conservatives Line Up Against Sperm Donors, But Lack the Power to Ban Them

WASHINGTON — A new documentary exploring the ethical implications of sperm donation is creating a buzz among religious audiences.

“Anonymous Father’s Day” delves into bioethics from the perspective of donor-conceived children who grow up not knowing their biological fathers. The film gives fodder to opponents of assisted reproductive technology, who argue the fertility “industry” has led to psychologically scarred children and the “commodification” of human life.

ART’s ethical implications are not solely a religious issue, and “Anonymous Father’s Day” makes no explicit religious claims. But its promotion of heterosexual marriage attracts religious audiences, who oppose the reproductive alternatives ART facilitates.

Jennifer Lahl, the writer, director and producer behind the film, recently held back-to-back screenings in Washington, D.C., at the conservative Christian-focused Family Research Council and the Catholic Information Center. Lahl plans future showings at Christian institutions.

This is the second film on gamete donation by Lahl, founder and president of The Center for Bioethics and Culture, a California-based nonprofit that studies beginning and end-of-life issues.

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